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产品信息
OSP00073W-100UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ Ig
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide from the cytoplasmic domain of human KCNE3 conjugated to blue carrier protein was used as the antigen
偶联物
形式
Lyophilized
浓度
Conc. Not Determined
保存液
whole serum
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: KCNE3.
靶标信息
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Associated with KCNC4/Kv3.4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: cardiac voltage-gated potassium channel accessory subunit; Minimum potassium ion channel-related peptide 2; MinK-related peptide 2; MiRP2; Potassium channel subunit beta MiRP2; potassium channel, voltage gated subfamily E regulatory beta subunit 3; Potassium voltage-gated channel subfamily E member 3; potassium voltage-gated channel, Isk-related family, member 3; potassium voltage-gated channel, Isk-related subfamily, gene 3; potassium voltage-gated channel, Isk-related subfamily, member 3; voltage-gated K+ channel subunit MIRP2
基因别名: 2210017H05Rik; HOKPP; HYPP; KCNE3; MiRP2
UniProt ID: (Human) Q9Y6H6, (Rat) Q9JJV7, (Mouse) Q9WTW2
Entrez Gene ID: (Human) 10008, (Rat) 63883, (Mouse) 57442
regulation of membrane repolarization
potassium ion transmembrane transport
positive regulation of voltage-gated calcium channel activity
negative regulation of delayed rectifier potassium channel activity
regulation of potassium ion transport
regulation of potassium ion transmembrane transport
negative regulation of voltage-gated potassium channel activity
transport
ion transport
potassium ion transport
regulation of ion transmembrane transport
