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KCNH4 Antibody (OSP00077W-100UL) in IHC (P)
IHC-P on paraffin sections of rat DRG. The animal was perfused using Autoperfuser at a pressure of 110 mmHg with 300 mL 4% FA and further post fixed overnight before being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions. Pr... View More
产品信息
OSP00077W-100UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Rat
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ Ig
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide from the c-terminal of rat KCNH4 (Potassium voltage-gated channel subfamily H member 4) conjugated to an immunogenic carrier protein was used as the antigen
偶联物
形式
Lyophilized
浓度
Conc. Not Determined
保存液
whole serum
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: KCNH4.
靶标信息
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. The gene is brain-specific, and located in the neocortex and the striatum. It may be involved in cellular excitability of restricted neurons in the central nervous system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: BEC2; Brain-specific eag-like channel 2; ELK channel 1; Ether-a-go-go-like potassium channel 1; Potassium voltage-gated channel subfamily H member 4; potassium voltage-gated channel, subfamily H (eag-related), member 4; rElk1; Voltage-gated delayed rectifier potassium channel KCNH4; Voltage-gated potassium channel subunit Kv12.3
基因别名: Bec2; Elk1; Elk3; Kcnh4
UniProt ID: (Rat) Q9R1T9
Entrez Gene ID: (Rat) 114032
