Osenses

KCNJ9 Polyclonal Antibody

产品信息

OSK00060W-100UL

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:300-1:2,000

免疫组化 (IHC)

1:300-1:2,000

其他PubMed (Misc)

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产品规格

种属反应

Human, Mouse, Rat

已发表种属

Not Applicable

宿主/亚型

Rabbit / Ig

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide from aa region 300-350 of human KCNJ9 (Kir3.3, GIRK3) conjugated to an immunogenic carrier protein was used as the antigen

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

Conc. Not Determined

保存液

whole serum

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Specificity of this antibody: KCNJ9.

靶标信息

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. [provided by RefSeq, Jul 2008].

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

The DNA sequence and biological annotation of human chromosome 1.

Nature

Gregory SG,Barlow KF,McLay KE,Kaul R,Swarbreck D,Dunham A,Scott CE,Howe KL,Woodfine K,Spencer CC,Jones MC,Gillson C,Searle S,Zhou Y,Kokocinski F,McDonald L,Evans R,Phillips K,Atkinson A,Cooper R,Jones C,Hall RE,Andrews TD,Lloyd C,Ainscough R,Almeida JP,Ambrose KD,Anderson F,Andrew RW,Ashwell RI,Aubin K,Babbage AK,Bagguley CL,Bailey J,Beasley H,Bethel G,Bird CP,Bray-Allen S,Brown JY,Brown AJ,Buckley D,Burton J,Bye J,Carder C,Chapman JC,Clark SY,Clarke G,Clee C,Cobley V,Collier RE,Corby N,Coville GJ,Davies J,Deadman R,Dunn M,Earthrowl M,Ellington AG,Errington H,Frankish A,Frankland J,French L,Garner P,Garnett J,Gay L,Ghori MR,Gibson R,Gilby LM,Gillett W,Glithero RJ,Grafham DV,Griffiths C,Griffiths-Jones S,Grocock R,Hammond S,Harrison ES,Hart E,Haugen E,Heath PD,Holmes S,Holt K,Howden PJ,Hunt AR,Hunt SE,Hunter G,Isherwood J,James R,Johnson C,Johnson D,Joy A,Kay M,Kershaw JK,Kibukawa M,Kimberley AM,King A,Knights AJ,Lad H,Laird G,Lawlor S,Leongamornlert DA,Lloyd DM,Loveland J,Lovell J,Lush MJ,Lyne R,Martin S,Mashreghi-Mohammadi M,Matthews L,Matthews NS,McLaren S,Milne S,Mistry S,Moore MJ,Nickerson T,O'Dell CN,Oliver K,Palmeiri A,Palmer SA,Parker A,Patel D,Pearce AV,Peck AI,Pelan S,Phelps K,Phillimore BJ,Plumb R,Rajan J,Raymond C,Rouse G,Saenphimmachak C,Sehra HK,Sheridan E,Shownkeen R,Sims S,Skuce CD,Smith M,Steward C,Subramanian S,Sycamore N,Tracey A,Tromans A,Van Helmond Z,Wall M,Wallis JM,White S,Whitehead SL,Wilkinson JE,Willey DL,Williams H,Wilming L,Wray PW,Wu Z,Coulson A,Vaudin M,Sulston JE,Durbin R,Hubbard T,Wooster R,Dunham I,Carter NP,McVean G,Ross MT,Harrow J,Olson MV,Beck S,Rogers J,Bentley DR,Banerjee R,Bryant SP,Burford DC,Burrill WD,Clegg SM,Dhami P,Dovey O,Faulkner LM,Gribble SM,Langford CF,Pandian RD,Porter KM,Prigmore E

Thu May 18 00:00:00 UTC 2006

Genomic structure and expression of human KCNJ9 (Kir3.3/GIRK3).

Biochemical and biophysical research communications

Vaughn J,Wolford JK,Prochazka M,Permana PA

Wed Aug 02 00:00:00 UTC 2000

Co-expression of human Kir3 subunits can yield channels with different functional properties.

Cellular signalling

Schoots O,Wilson JM,Ethier N,Bigras E,Hebert TE,Van Tol HH

Wed Dec 01 00:00:00 UTC 1999

生物信息学

蛋白别名: G protein-activated inward rectifier potassium channel 3; G protein-coupled inward rectifier potassium channel; GIRK-3; Inward rectifier K(+) channel Kir3.3; inwardly rectifier K(+) channel Kir3.3; inwardly rectifier K+ channel KIR3.3; Potassium channel, inwardly rectifying subfamily J member 9; potassium channel, inwardly rectifying subfamily J, member 9; potassium inwardly-rectifying channel, subfamily J, member 9

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基因别名: 1700085N21Rik; GIRK3; KCNJ9; KIR3.3; mbGIRK3

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UniProt ID: (Human) Q92806, (Rat) Q63511, (Mouse) P48543

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Entrez Gene ID: (Human) 3765, (Rat) 116560, (Mouse) 16524

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功能

inward rectifier potassium channel activity protein binding G-protein activated inward rectifier potassium channel activity molecular_function PDZ domain binding voltage-gated ion channel activity ion channel transporter

参与通路

potassium ion import regulation of ion transmembrane transport biological_process transport ion transport potassium ion transport