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KCNK4(TRAAK) Antibody (APC-108-200UL) in IHC
Expression of KCNK4in rat cerebellum - Immunohistochemical staining of rat cerebellum using Anti-KCNK4 (TRAAK) Antibody (#APC-108 ). A. KCNK4 channel appears in Purkinje neuronal processes (red). B. Staining of Purkinje nerve cells with mouse Anti-calbindin D28K (a calcium binding protein, green). C. Confocal merge of KCNK4 channel and calbindin D28K demonstrates the co-localization of these proteins.
产品信息
APC-108-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
NLAFIDESSDTQSERGC, corresponding to amino acid residues 343-359 of human KCNK4, Intracellular, C-terminus
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The encoded protein homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: K2P4.1; K2P4.1 potassium channel; KT4.1b; Potassium channel subfamily K member 4; potassium channel, subfamily K, member 4; potassium channel, two pore domain subfamily K, member 4; potassium inwardly-rectifying channel subfamily K member 4; potassium inwardly-rectifying channel, subfamily K, member 4; protein expressed in male leptotene and zygotene spermatocytes 622; TRAAK; TWIK-related arachidonic acid-stimulated potassium channel protein; two pore K(+) channel KT4.1; two pore K+ channel KT4.1; Two pore potassium channel KT4.1
基因别名: K2p4.1; KCNK4; KT4.1; MLZ-622; Tex40; TRAAK; TRAAK1; TRAAKt
UniProt ID: (Human) Q9NYG8, (Mouse) O88454, (Rat) G3V8V5
Entrez Gene ID: (Human) 50801, (Mouse) 16528, (Rat) 116489
potassium ion transport
memory
sensory perception of pain
stabilization of membrane potential
regulation of ion transmembrane transport
sensory perception of temperature stimulus
detection of mechanical stimulus involved in sensory perception of touch
cellular response to mechanical stimulus
cellular response to fatty acid
cellular response to alkaline pH
cellular response to temperature stimulus
potassium ion transmembrane transport
transport
ion transport
