Invitrogen

KCNMA1 Polyclonal Antibody

KCNMA1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 1

KCNMA1 Antibody (PA5-33872) in IHC (P)

Immunohistochemistry analysis of KCNMA1 in human breast, vessel. Samples were incubated with KCNMA1 polyclonal antibody (Product # PA5-33872). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Product Image Gallery

产品信息

PA5-33872

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

10-20 µg/mL

产品规格

种属反应

Bovine, Chicken, Horse, Hamster, Human, Mouse, Non-human primate, Pig, Rabbit, Rat, Xenopus, Zebrafish

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic 15 amino acid peptide from internal region of human KCNMA1.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS

内含物

0.1% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2551241

靶标信息

Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: big potassium channel alpha subunit; BK alpha; BK channel; BK channel alpha subunit; BKCA alpha; BKCA alpha subunit; bSlo; calcium-activated potassium channel alpha subunit; Calcium-activated potassium channel subunit alpha-1; Calcium-activated potassium channel, subfamily M subunit alpha-1; hypothetical protein; K(VCA)alpha; KCa1.1; large conductance calcium-activated potassium channel alpha subunit; Maxi K channel; maxi-K channel alpha subunit; maxi-K channel HSLO; MaxiK; MaxiK alpha subunit; mSlo1; potassium channel, calcium activated large conductance subfamily M alpha, member 1; potassium large conductance calcium-activated channel, subfamily M, alpha member 1; RbSlo; slo; Slo homolog; Slo-alpha; Slo1; slowpoke; Slowpoke homolog; stretch-activated Kca channel

查看更多收起

基因别名: 5730414M22Rik; bA205K10.1; BKCA; BKTM; cSlo; hSlo; I79_002194; KCa1.1; KCNMA; KCNMA1; KCNMA1b; KCNMA1c; MaxiK; mSlo; mSLO1; RBSLO1; SAKCA; SLO; SLO-ALPHA; SLO1