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KDELR1 Antibody (MA5-45149) in WB
Western Blot analysis of Rat tissue lysate showing detection of KDEL Receptor protein. Load: 15 µg. Blocking: 1.5% BSA for 30 minutes at RT. Samples were incubated with KDEL Receptor monoclonal antibody (Product # MA5-45149) at 1:1,000 for 2 hours at RT, followed by Sheep Anti-Mouse IgG: HRP for 1 hour at RT.
产品信息
MA5-45149
应用
建议稀释比
已发表文章
产品规格
种属反应
Bovine,
Dog,
Chicken,
Fruit fly,
Hamster,
Human,
Mouse,
Non-human primate,
Sheep,
Pig,
Rabbit,
Rat,
Xenopus
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
KR-10
抗原
A 21 residue synthetic peptide (amino acids 192-212) based on the bovine KDEL receptor and the peptide coupled to KLH
偶联物
激发/发射光谱
651/660 nm
查看光谱
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
95.64mM phosphate/2.48mM MES, pH 7.2, with 0.5M EDTA
内含物
no preservative
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2931603
产品详细信息
1 µg/mL was sufficient for detection of KDEL receptor in 20 µg monkey Vero cell lysate by colorimetric immunoblot analysis using Goat Anti-Mouse IgG:AP as the secondary.|Detects approximately 25kDa.
靶标信息
KDELR1 (KDEL Endoplasmic Reticulum Protein Retention Receptor 1) is a Protein Coding gene. Diseases associated with KDELR1 include Syndromic X-Linked Intellectual Disability 94 and Myopathy, Centronuclear, 1. Among its related pathways are Transport to the Golgi and subsequent modification and Activation of cAMP-Dependent PKA. Gene Ontology (GO) annotations related to this gene include ER retention sequence binding and KDEL sequence binding. An important paralog of this gene is KDELR2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ER lumen protein retaining receptor 1; ER lumen protein-retaining receptor 1; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1; KDEL endoplasmic reticulum protein retention receptor 1; KDEL receptor 1; KDEL receptor-like protein; Putative MAPK-activating protein PM23
基因别名: 8030486F04Rik; AW215843; ERD2; ERD2.1; HDEL; I79_020931; KDELR; KDELR1; PM23
UniProt ID: (Human) P24390, (Bovine) P33946, (Mouse) Q99JH8, (Rat) Q569A6
protein retention in ER lumen
intracellular protein transport
ER to Golgi vesicle-mediated transport
retrograde vesicle-mediated transport, Golgi to ER
T cell cytokine production
protein transport
T cell differentiation
T cell apoptotic process
transport
biological_process
vesicle-mediated transport
