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Recommended positive controls: HeLa.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a 134 kDa protein named strumpellin that is predicted to have multiple transmembrane domains and a spectrin-repeat-containing domain. This ubiquitously expressed gene has its highest expression in skeletal muscle. The protein is named for Strumpell disease; a form of hereditary spastic paraplegia (HSP). Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive, lower extremity spasticity caused by axonal degeneration in the terminal portions of the longest descending and ascending corticospinal tracts. More than 30 loci (SPG1-33) have been implicated in hereditary spastic paraplegia diseases.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Strumpellin; WASH complex subunit 5; WASH complex subunit strumpellin
基因别名: KIAA0196; RTSC; RTSC1; SPG8; WASHC5
UniProt ID: (Human) Q12768
Entrez Gene ID: (Human) 9897