Invitrogen

KIF18A Polyclonal Antibody

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抗体检测数据 (5)
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KIF18A Antibody in Immunocytochemistry (ICC/IF)

KIF18A Antibody in Immunocytochemistry (ICC/IF)

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KIF18A Antibody (PA5-58728) in ICC/IF

Immunofluorescent staining of KIF18A in human cell line U-2 OS using a KIF18A Polyclonal Antibody (Product # PA5-58728) shows localization to cytosol, microtubules and cytokinetic bridge.

KIF18A Antibody in Immunocytochemistry (ICC/IF)

KIF18A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

KIF18A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

KIF18A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

KIF18A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

KIF18A Antibody in Immunohistochemistry (IHC)

KIF18A Antibody in Immunohistochemistry (IHC)

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KIF18A Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent staining of KIF18A in human cell line U-2 OS using a KIF18A Polyclonal Antibody (Product # PA5-58728) shows localization to cytosol, microtubules and cytokinetic bridge.

KIF18A Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of KIF18A in human testis using KIF18A Polyclonal Antibody (Product # PA5-58728) shows strong cytoplasmic positivity in cells in seminiferous ducts.

KIF18A Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of KIF18A in human fallopian tube using KIF18A Polyclonal Antibody (Product # PA5-58728) shows strong cytoplasmic positivity in glandular cells.

KIF18A Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of KIF18A in human rectum using KIF18A Polyclonal Antibody (Product # PA5-58728) shows very strong cytoplasmic positivity in glandular cells.

KIF18A Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of KIF18A in human kidney using KIF18A Polyclonal Antibody (Product # PA5-58728) shows strong cytoplasmic positivity in cells in tubules.

KIF18A Antibody in Immunohistochemistry (IHC) — FIGURE 6 Knockdown of KIF18A impaired the tumor growth of GBM cells in mice. (A) U87 cells infected with KIF18A or shRNA control plasma were repopulated into nude mice. After 2 weeks, tumors were drained and tumor size was measured weekly ( n = three groups). Tumor growth curves estimated three tumors. (B) Analysis shows that KIF18A is expressed in control or non-KIF18A tumor tissue from mice. (C) IHC analysis shows that Ki67 is expressed in control tissues or tissues lacking KIF18A. Results are expressed as overall standard deviation, * p < 0.05.

KIF18A Antibody in Immunohistochemistry (IHC) — FIGURE 3 KIF18A expression in human GBM tissues. (A) Expression levels of KIF18A in human GBM and normal tissues (GBM: glioblastoma, * p < 0.05). (B) Immunohistochemical (IHC) staining of KIF18A protein in human GBM tissues (x100 and x200 magnification, resp.). (C) IHC staining of KIF18A in the adjacent tissues (x100 and x200 magnification, resp. ).

产品信息

PA5-58728

应用

建议稀释比

已发表文章

免疫组化 (IHC)

-

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免疫组化（石蜡） (IHC (P))

1:20-1:50

-

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

-

产品规格

种属反应

Human

已发表种属

Not Applicable

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human KIF18A. Recombinant protein control fragment (Product #RP-97337).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.05 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2643089

产品详细信息

Immunogen sequence: LHCHHLHLQN KDLKAQIRHM MDLACLQEQQ HRQTEAVLNA LLPTLRKQYC TLKEAGLSNA AFESDFKEIE HLVERKKVVV WADQTAEQPK QND

Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 82%.

靶标信息

May have a role in a signaling pathway. Could act as a tumor suppressor.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

The Proliferation of Glioblastoma Is Contributed to Kinesin Family Member 18A and Medical Data Analysis of GBM.

Frontiers in genetics

Wang LB,Zhang XB,Liu J,Liu QJ

Published figure using KIF18A polyclonal antibody (Product # PA5-58728) in Immunohistochemistry

Sat Jul 16 00:00:00 UTC 2022

生物信息学

蛋白别名: Kinesin-like protein KIF18A; Marrow stromal KIF18A; MS-KIF18A; protein phosphatase 1, regulatory subunit 99

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基因别名: KIF18A; MS-KIF18A; OK/SW-cl.108; PPP1R99

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UniProt ID: (Human) Q8NI77

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Entrez Gene ID: (Human) 81930

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actin binding protein binding ATP binding microtubule binding ATP-dependent microtubule motor activity, plus-end-directed ubiquitin binding microtubule plus-end binding tubulin-dependent ATPase activity microtubule binding motor protein

retrograde vesicle-mediated transport, Golgi to ER microtubule-based movement microtubule depolymerization sister chromatid cohesion mitotic metaphase plate congression male meiosis protein transport antigen processing and presentation of exogenous peptide antigen via MHC class II regulation of microtubule cytoskeleton organization seminiferous tubule development