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KIR3DS1 Antibody (PA5-97295) in IHC (P)
Immunohistochemistry analysis of KIR3DS1 in paraffin-embedded human mammary cancer. Samples were incubated with KIR3DS1 Polyclonal antibody (Product # PA5-97295) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-97295
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 80-340 of human KIR3DS1 (NP_0010770081)
偶联物
形式
Liquid
浓度
0.97 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2809097
产品详细信息
Immunogen sequence: FNMSPVTTAH AGNYTCRGSH PHSPTGWSAP SNPMVIMVTG NHRKPSLLAH PGPLVKSGER VILQCWSDIM FEHFFLHKEW ISKDPSRLVG QIHDGVSKAN FSIGSMMRAL AGTYRCYGSV THTPYQLSAP SDPLDIVVTG LYEKPSLSAQ PGPKVQAGES VTLSCSSRSS YDMYHLSREG GAHERRLPAV RKVNRTFQAD FPLGPATHGG TYRCFGSFRH SPYEWSDPSD PLLVSVTGNP SSSWPSPTEP SSKSGNLRHL H; Positive Samples: Jurkat, A-549, THP-1, BT-474, B-cell, Mouse liver, Mouse kidney, Mouse pancreas, Rat liver; Cellular Location: Cell membrane, Single-pass type I membrane protein
靶标信息
The killer immunoglobulin-like receptors (KIRs) on natural killer (NK) cells regulate the inhibition and activation of NK-cell responses through recognition of human leukocyte antigen (HLA) class I molecules. KIR3DL1, a receptor for HLA-B antigens with the Bw4 allele, transmits an inhibitory signal to prevent killer cell-mediated cytoxicity. KIR3DL1 encodes a 444 amino acid type I transmembrane protein, containing three immunoglobulin-like C2-type domains.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Killer cell immunoglobulin-like receptor 3DS1; killer cell immunoglobulin-like receptor KIR3DS1; killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1; killer Ig receptor; MHC class I NK cell receptor; natural killer cell receptor; Natural killer-associated transcript 10; NKAT-10
基因别名: CD158E2; KIR-123FM; KIR-G1; KIR3DS1; NKAT-10; NKAT10
UniProt ID: (Human) Q14943
Entrez Gene ID: (Human) 3813
