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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLRMRVPALL VLLFCFRGRA GPSPHFLQQP EDLVVLLGEG GAQASLGRRA SASFSEQKNL MRIPGSSDGS SSRGPEEEET GSREDRGPIV HTDHSDLVLE EEGTLETKDP TNGYYKVRGV SVSLSLGEAP GGGLFLPPPS PLGPPGTPTF YDFNPHLGMV PPCRLYRARA GYLTTPHPRA FTSYIKPTSF GPPDLAPGTP PFPYAAFPTP SHPRLQTHV
This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin are regulated by a bidirectional promoter.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp564A1164; Kin of IRRE-like protein 2; Kin of irregular chiasm-like protein 2; MGC15718; nephrin-like 3; nephrin-like gene 1; Nephrin-like protein 3
基因别名: FILTRIN; KIRREL2; NEPH3; NLG1; UNQ5827/PRO19646
UniProt ID: (Human) Q6UWL6
Entrez Gene ID: (Human) 84063