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KLF2 Antibody (PA5-120456) in WB
Western blot analysis of KLF2 in extracts of various cell lines. Samples were incubated with KLF2 Polyclonal antibody (Product # PA5-120456) using a dilution of 1:2,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-120456
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human KLF2 (NP_057354.1).
偶联物
形式
Liquid
浓度
2.72 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914028
产品详细信息
Positive test controls include: A-549, PC-3, U-251MG. The target is usually found in the following locations: Nucleus.
Immunogen sequence: LDAPLGPALH GRFLLAPPGR LVKAEPPEAD GGGGYGCAPG LTRGPRGLKR EGAPGPAASC MRGPGGRPPP PPDTPPLSPD GPARLPAPGP RASFPPPFGG P
靶标信息
KLF2 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 3 C2H2-type zinc fingers. KLF2 binds to the CACCC box in the beta-globin gene promoter and activates transcription.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Krueppel-like factor 2; Kruppel-like factor 2 (lung); Kruppel-like factor LKLF; Lung krueppel-like factor; lung Kruppel-like factor; lung Kruppel-like zinc finger transcription factor
基因别名: KLF2; LKLF
UniProt ID: (Human) Q9Y5W3
Entrez Gene ID: (Human) 10365
cell morphogenesis
in utero embryonic development
transcription, DNA-templated
negative regulation of interleukin-6 production
multicellular organism growth
positive regulation of transcription from RNA polymerase II promoter in response to stress
regulation of gene expression, epigenetic
erythrocyte maturation
positive regulation of nitric oxide biosynthetic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of protein metabolic process
Type I pneumocyte differentiation
cellular response to hydrogen peroxide
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to cycloheximide
cellular response to laminar fluid shear stress
cellular response to peptide
