Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
MA5-15700
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
3A8
抗原
Purified recombinant fragment of human KLHL1 expressed in E. Coli.
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
ascites
内含物
0.03% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_10984316
产品详细信息
MA5-15700 targets KLHL1 in indirect ELISA, IF and WB applications and shows reactivity with Human, Mouse and Rat samples.
The MA5-15700 immunogen is purified recombinant fragment of human KLHL1 expressed in E. Coli.
MA5-15700 detects KLHL1 which has a predicted molecular weight of approximately 82kDa. In Western blot, MA5-15700 did not detect KLHL1 in whole rat brain lysates, but detected KLHL1 in hippocampal neuronal cell lysates.
靶标信息
The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin-organizing proteins. Based on the presence of anti-sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: FLJ30047; kelch-l like; kelch-like 1; kelch-like family member 1; Kelch-like protein 1; Mayven-related protein 2; RP11-394C23.1
基因别名: KIAA1490; KLHL1; mKIAA1490; MRP2
UniProt ID: (Human) Q9NR64, (Mouse) Q9JI74
Entrez Gene ID: (Human) 57626, (Rat) 290426, (Mouse) 93688
