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KMO Antibody (PA5-100019) in IHC (P)
Immunohistochemistry analysis of KMO in human normal tissues adjacent to liver cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with KMO polyclonal antibody (Product # PA5-100019) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-100019
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human KMO(Accession O15229), corresponding to amino acid residues K333-E383.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2815549
产品详细信息
Antibody detects endogenous levels of total KMO.
靶标信息
Kynurenine 3-monooxygenase (KMO; EC 1.14.13.9) is an NADPH-dependent flavin monooxygenase that catalyzes the hydroxylation of the L-tryptophan metabolite L-kynurenine to form L-3-hydroxykynurenine.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: KMO; kmo {ECO:0000312|RGD:620610}; Kynurenine 3-hydroxylase; kynurenine 3-hydroxylase {ECO:0000255|HAMAP-Rule:MF_03018}; Kynurenine 3-monooxygenase; kynurenine 3-monooxygenase {ECO:0000255|HAMAP-Rule:MF_03018}
基因别名: AI046660; dJ317G22.1; KMO
UniProt ID: (Human) O15229, (Mouse) Q91WN4, (Rat) O88867
Entrez Gene ID: (Human) 8564, (Mouse) 98256, (Rat) 59113
tryptophan catabolic process
response to salt stress
tryptophan catabolic process to kynurenine
NAD metabolic process
quinolinate biosynthetic process
'de novo' NAD biosynthetic process from tryptophan
anthranilate metabolic process
secondary metabolite biosynthetic process
oxidation-reduction process
kynurenine metabolic process
metabolic process
pyridine nucleotide biosynthetic process
