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KMO Antibody (PA5-35353) in IHC (P)
Immunohistochemistry analysis of KMO in formalin-fixed and paraffin-embedded human hepatocarcinoma. Samples were incubated with KMO polyclonal antibody (Product # PA5-35353) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Details
PA5-35353
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 155-182 amino acids from the central region of human KMO
Conjugate
Form
Liquid
Concentration
2.0 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2552663
Target Information
Kynurenine 3-monooxygenase (KMO; EC 1.14.13.9) is an NADPH-dependent flavin monooxygenase that catalyzes the hydroxylation of the L-tryptophan metabolite L-kynurenine to form L-3-hydroxykynurenine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: KMO; Kynurenine 3-hydroxylase; Kynurenine 3-monooxygenase
Gene Aliases: AI046660; dJ317G22.1; KMO
UniProt ID: (Human) O15229, (Mouse) Q91WN4
Entrez Gene ID: (Human) 8564, (Mouse) 98256
tryptophan catabolic process
response to salt stress
tryptophan catabolic process to kynurenine
NAD metabolic process
quinolinate biosynthetic process
'de novo' NAD biosynthetic process from tryptophan
anthranilate metabolic process
secondary metabolite biosynthetic process
oxidation-reduction process
kynurenine metabolic process
metabolic process
pyridine nucleotide biosynthetic process
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