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产品信息
PA5-67359
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2664133
产品详细信息
Immunogen sequence: TPPTMSQPTFP MVPQQLQHQQ HTTVISGHTS PVRMPSLPGW QPNSAPAHLP LNPPRIQPPI AQLPIKTCTP APGTVSNANP Q
Highest antigen sequence identity to the following orthologs - mouse 88%, rat 33%.
靶标信息
Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2.1.1.43; ALR-like protein; Histone-lysine N-methyltransferase 2C; histone-lysine N-methyltransferase MLL3; histone-lysine N-methyltransferase, H3 lysine-4 specific; Homologous to ALR protein; lysine (K)-specific methyltransferase 2C; Lysine N-methyltransferase 2C; Myeloid/lymphoid or mixed-lineage leukemia protein 3
基因别名: HALR; KIAA1506; KMT2C; MLL3
UniProt ID: (Human) Q8NEZ4
Entrez Gene ID: (Human) 58508
