Invitrogen

KTN1 Polyclonal Antibody

KTN1 Antibody in Immunocytochemistry (ICC/IF)

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KTN1 Antibody (PA5-51847) in ICC/IF

Immunofluorecent analysis of KTN1 in human cell line U-251 MG using KTN1 Polyclonal Antibody (Product # PA5-51847). Staining shows localization to endoplasmic reticulum.

KTN1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

KTN1 Antibody in Immunohistochemistry (IHC)

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KTN1 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of KTN1 demonstrates antibody specificity. Immunohistochemical analysis of KTN1 using anti-KTN1 Polyclonal Antibody (Product # PA5-51847), shows significant staining of KTN1 in human testis and shows minimal or weak staining in human bone marrow tissues. The relative expression levels of KTN1 within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-51847

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human KTN1. Recombinant protein control fragment (Product #RP-89045).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2643234

产品详细信息

Immunogen sequence: ETLMVPSKRQ EALPLHQETK QESGSGKKKA SSKKQKTENV FVDEPLIHAT TYIPLMDNAD SSPVVDKREV IDLLKPDQVE GIQKSGTKKL KTETDKENAE VKFKDFLLSL KTMMFSEDEA LCVVDLLKEK SGVIQ

Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 75%.

靶标信息

Various cellular organelles and vesicles are transported along the microtubules in the cytoplasm. Likewise, membrane recycling of the endoplasmic reticulum (ER), Golgi assembly at the microtubule organizing center, and alignment of lysosomes along microtubules are all related processes. The transport of organelles requires a special class of microtubule-associated proteins (MAPs). One of these is the molecular motor kinesin an ATPase that moves vesicles unidirectionally toward the plus end of the microtubule. Another such MAP is kinectin, a large integral ER membrane protein. Antibodies directed against kinectin have been shown to inhibit its binding to kinesin.

仅用于科研。不用于诊断过程。未经明确授权不得转售。