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产品信息
PA5-40815
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the N-terminal of human KCNA5 (aa 72-121).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2609184
产品详细信息
Peptide sequence: DPGVRPLPPL PEELPRPRRP PPEDEEEEGD PGLGTVEDQA LGTASLHHQR
Sequence homology: Human: 100%; Mouse: 93%; Rat: 93%
靶标信息
In neurons voltage-dependent potassium channels are key determinants of the resting membrane potential and of membrane excitability, conditioning the frequency, and shape of action potential.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cardiac potassium channel; HPCN1; insulinoma and islet potassium channel; MGC117058; MGC117059; potassium channel 1; potassium channel, voltage gated shaker related subfamily A, member 5; Potassium voltage-gated channel subfamily A member 5; potassium voltage-gated channel, shaker-related subfamily, member 5; Voltage-gated potassium channel HK2; voltage-gated potassium channel protein Kv1.5; Voltage-gated potassium channel subunit Kv1.5
基因别名: ATFB7; HCK1; HK2; HPCN1; KCNA5; KV1.5; PCN1
UniProt ID: (Human) P22460
Entrez Gene ID: (Human) 3741
receptor binding
delayed rectifier potassium channel activity
protein binding
outward rectifier potassium channel activity
potassium channel inhibitor activity
protein kinase binding
alpha-actinin binding
voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization
voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
voltage-gated potassium channel activity involved in SA node cell action potential repolarization
scaffold protein binding
voltage-gated ion channel
response to hypoxia
potassium ion transport
Notch signaling pathway
response to mechanical stimulus
response to organic substance
regulation of vasoconstriction
regulation of membrane potential
response to hydrogen peroxide
regulation of potassium ion transport
negative regulation of potassium ion transport
regulation of insulin secretion
protein homooligomerization
negative regulation of cytosolic calcium ion concentration
potassium ion homeostasis
response to hyperoxia
membrane hyperpolarization
regulation of atrial cardiac muscle cell membrane repolarization
potassium ion export
potassium ion transmembrane transport
atrial cardiac muscle cell action potential
membrane repolarization during bundle of His cell action potential
membrane repolarization during SA node cell action potential
regulation of heart rate by cardiac conduction
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of myoblast proliferation
