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产品信息
APC-011-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
DLGGKRLGIEDAAGLGGPDGK(C), corresponding to amino acid residues 184-204 of rat KV3.2, Intracellular, N-terminal domain
偶联物
形式
Lyophilized
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA, 5% sucrose
内含物
0.025% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels. The subunits vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming alpha subunits, which include the KV1, KV2, KV3, KV4 and KV9 proteins, as well as accessory subunits that modify the gating properties of the coexpressed KV subunits. KV3.2 is a multipass membrane protein that regulates the voltage-dependent K+ permeability of excitable membranes. The tail of KV3.2 may be influential in the targeting of the channel to specific subcellular compartments and/or the regulation of channel activity.
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生物信息学
蛋白别名: Potassium channel voltage-gated Shaw-related subfamily C member 2; potassium channel, voltage gated Shaw related subfamily C, member 2; potassium voltage gated channel, Shaw-related subfamily, member 2; Potassium voltage-gated channel subfamily C member 2; potassium voltage-gated channel, Shaw-related subfamily, member 2; Shaw-like potassium channel; Voltage-gated potassium channel KCNC2; Voltage-gated potassium channel Kv3.2; Voltage-gated potassium channel subunit Kv3.2
基因别名: AW047325; B230117I07; KCNC2; KShIIIA; KV3.2
UniProt ID: (Human) Q96PR1, (Rat) P22462, (Mouse) Q14B80
Entrez Gene ID: (Human) 3747, (Rat) 246153, (Mouse) 268345
response to light intensity
response to organic cyclic compound
response to amine
globus pallidus development
response to magnesium ion
nitric oxide-cGMP-mediated signaling pathway
response to ethanol
regulation of insulin secretion
protein homooligomerization
protein heterooligomerization
cellular response to ammonium ion
cellular response to nitric oxide
potassium ion transmembrane transport
cellular response to toxic substance
positive regulation of potassium ion transmembrane transport
response to nerve growth factor
action potential
response to toxic substance
ion transmembrane transport
transport
ion transport
potassium ion transport
regulation of ion transmembrane transport
transmembrane transport
