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Product Details
PA5-115450
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human KCND1(Accession Q9NSA2), corresponding to amino acid residues V518-S568.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2900086
Product Specific Information
Antibody detects endogenous levels of total KCND1.
Target Information
The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming alpha-subunits (KV alpha), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KV beta subunits that modify the gating properties of the coexpressed KV alpha subunits. Differences exist in the patterns of trafficking, biosynthetic processing and surface expression of the major KV1 subunits (KV1. 1, KV1. 2 and KV1. 4) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A-type voltage-gated potassium channel KCND1; mShal; potassium channel, voltage gated Shal related subfamily D, member 1; Potassium voltage-gated channel subfamily D member 1; potassium voltage-gated channel, Shal-related subfamily, member 1; Shal-type potassium channel; Shal-type potassium channel KCND1; Voltage-gated potassium channel subunit Kv4.1
Gene Aliases: 1110037K09Rik; Kca2-1; KCND1; KV4.1; mShal1; Shal; Shal1
UniProt ID: (Human) Q9NSA2, (Mouse) Q03719
Entrez Gene ID: (Human) 3750, (Mouse) 16506
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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