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产品信息
MA5-31782
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
5B11B9
抗原
Purified recombinant fragment of human KCND2 (AA: 27-184) expressed in E. coli.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2787405
产品详细信息
MA5-31782 has been tested in indirect ELISA.
靶标信息
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes-shaker, shaw, shab, and shal-have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: A-type voltage-gated potassium channel KCND2; potassium channel, voltage gated Shal related subfamily D, member 2; Potassium voltage-gated channel subfamily D member 2; Voltage-gated potassium channel subunit Kv4.2; voltage-sensitive potassium channel
基因别名: KCND2; KIAA1044; KV4.2; RK5
UniProt ID: (Human) Q9NZV8
Entrez Gene ID: (Human) 3751
