Invitrogen

KYNU Polyclonal Antibody

KYNU Antibody in Immunocytochemistry (ICC/IF)

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KYNU Antibody (PA5-83205) in ICC/IF

Immunofluorecent analysis of KYNU in human cell line A549 using KYNU Polyclonal Antibody (Product # PA5-83205). Staining shows localization to nucleoplasm and cytosol.

KYNU Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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KYNU Antibody — Relative expression in western blot: Antibody specificity was demonstrated by detection of known differential basal expression of the target across tissue/cell models. Expression of KYNU was observed specifically in A-549 cells and in HEK293 cells using anti-KYNU Polyclonal Antibody (Product #PA5-83205) in western blot. The relative expression levels of KYNU within each cell line is shown using RNA-Seq. {RE}

产品信息

PA5-83205

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human KYNU. Recombinant protein control fragment (Product #RP-89606).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2790361

产品详细信息

Immunogen sequence: YAIESQLQLH GLNIEESMRM IKPREGEETL RIEDILEVIE KEGDSIAVIL FSGVHFYTGQ HFNIPAITKA GQAKGCYVGF DLAHAVGNVE LYLHDWGVDF ACWCSYKYLN AGAGGIAGAF IHEKHAHTIK PALVGWFGHE LSTRFK

靶标信息

Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene. Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。