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Positive Control: Mouse brain tissue lysate, human skin tissue lysate, K562 cell lysate.
Subcellular Location: Secreted; Golgi apparatus.
Hippostasin, also known as KLK11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. Hippostasin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of KLK11 were found in 70% of women with ovarian cancer and in 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Hippostasin; hK11; kallikrein 11; Kallikrein-11; kallikrein-related peptidase 11; Kallikrein11; protease, serine, 20; Serine protease 20; Trypsin-like protease
基因别名: 2310015I08Rik; KLK11; PRSS20; TLSP; UNQ649/PRO1279
UniProt ID: (Human) Q9UBX7, (Mouse) Q9QYN3
Entrez Gene ID: (Human) 11012, (Mouse) 56538