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In direct ELISAs, less than 10% cross-reactivity with recombinant human (rh) Kallikrein 1, rhKallikrein 3, rhKallikrein 5, and rhKallikrein 9 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Hippostasin, also known as KLK11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. Hippostasin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of KLK11 were found in 70% of women with ovarian cancer and in 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.
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蛋白别名: Hippostasin; hK11; kallikrein 11; Kallikrein-11; kallikrein-related peptidase 11; Kallikrein11; Serine protease 20; Trypsin-like protease
基因别名: KLK11; PRSS20; TLSP; UNQ649/PRO1279
UniProt ID: (Human) Q9UBX7
Entrez Gene ID: (Human) 11012