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Immunogen sequence: AASHDQDIML LRLARPAKLS ELIQPLPLER DCSANTTSCH ILGWGKTADG DFPDTIQCAY IHLVSREECE HAYPGQITQN MLCAGDEKYG KDSCQGDSGG PLVCGDHLRG LVSWGNIPCG SKEKPGVYTN VCRYTNWIQK TIQAK; Positive Samples: HT-29; Cellular Location: Cytoplasm, Microsome, Mitochondrion, Nucleus, nucleolus
Kallikreins, including Kallikrein 6, are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK6 enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: kallikrein 6; kallikrein 7; Kallikrein-6; Kallikrein6; MGC9355; Neurosin; Protease M; Serine protease 18; Serine protease 9; SP59; Zyme
基因别名: Bssp; hK6; KLK6; Klk7; PRSS18; PRSS9; SP59
UniProt ID: (Human) Q6H301
Entrez Gene ID: (Human) 5653