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Kallikrein 8 Antibody (MA5-29381) in WB
Western Blot using Kallikrein 8 Recombinant Rabbit Monoclonal Antibody (140) (Product # MA5-29381) at 1:500 dilution. Lane A: A431 Whole Cell Lysate. Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG H&L (DyLight™ 800) at 1:10,000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 28 kDa. Observed band size: 35 kDa. (We are unsure of the identity of these extra bands).
产品信息
MA5-29381
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
140
抗原
Recombinant Human KLK8/Kallikrein 8 Protein (Met1-Gly260)
偶联物
形式
Liquid
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2785253
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human KLK8/Kallikrein 8.
靶标信息
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: H NRPN; hK8; Kallikrein-8; kallikrein-related peptidase 8; Kallikrein8; Neuropsin; NP; Ovasin; PRO322; Serine protease 19; Serine protease TADG-14; Tumor-associated differentially expressed gene 14 protein; UNQ283
基因别名: HNP; KLK8; NP; NRPN; PRSS19; TADG14; UNQ283/PRO322
UniProt ID: (Human) O60259
Entrez Gene ID: (Human) 11202
