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Kir2.2 (KCNJ12) Antibody (PA5-116581) in WB
Western blot analysis of Kir2.2 (KCNJ12) in extracts of various cell lines. Samples were incubated with Kir2.2 (KCNJ12) Polyclonal antibody (Product # PA5-116581) using a dilution of 1:300, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
产品信息
PA5-116581
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 354-433 of human KCNJ12 (NP_0662922)
偶联物
形式
Liquid
浓度
1.74 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2901212
产品详细信息
Positive Samples: Mouse brain, Rat brain
Immunogen sequence: TPRCSAKDLV ENKFLLPSAN SFCYENELAF LSRDEEDEAD GDQDGRSRDG LSPQARHDFD RLQAGGGVLE QRPYRRESEI
靶标信息
Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATP-sensitive inward rectifier potassium channel 12; Inward rectifier K(+) channel Kir2.2; IRK-2; Potassium channel, inwardly rectifying subfamily J member 12; potassium inwardly-rectifying channel, subfamily J, member 12
基因别名: IRK-2; IRK2; Kcnj12; Kir2.1; Kir2.2; MB-IRK2
UniProt ID: (Mouse) P52187
Entrez Gene ID: (Mouse) 16515, (Rat) 117052
