Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 10
Kir2.3 (KCNJ4) Antibody (PA5-102023) in ICC/IF
Immunocytochemistry analysis of Kir2.3 (KCNJ4) in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with Kir2.3 (KCNJ4) polyclonal antibody (Product # PA5-102023) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 co... View More
产品信息
PA5-102023
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human KCNJ4(Accession P48050), corresponding to amino acid residues R252-Q302.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2851454
产品详细信息
Antibody detects endogenous levels of total KCNJ4.
靶标信息
Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: BIR11; Brain inwardly rectifying K(+) channel 2; Hippocampal inward rectifier; hippocampal inward rectifier potassium channel; HIR; HIRK2; HRK1; Inward rectifier K(+) channel Kir2.3; Inward rectifier potassium channel 4; IRK-3; IRK3; Kir 2.3; Potassium channel, inwardly rectifying subfamily J member 4; potassium channel, inwardly rectifying subfamily J, member 4; potassium inwardly-rectifying channel, subfamily J, member 4
基因别名: HIR; HIRK2; HRK1; IRK-3; IRK3; Kcnf2; KCNJ4; Kir2.3; MB-IRK3
UniProt ID: (Human) P48050, (Rat) P52190
Entrez Gene ID: (Human) 3761, (Mouse) 16520, (Rat) 116649
