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Immunogen sequence: IFTLSVPFPT PLEAEIAHGS LAPDAEPHQR VVGKDLTVSG RILVVRWKAE DCRLLRISVI NFLDQLSLVV RTMQRFG
Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 71%.
This gene belongs to the ESO/LAGE gene family, members of which are clustered together on chromosome Xq28, and have similar exon-intron structures. Unlike the other family members which are normally expressed only in testis and activated in a wide range of human tumors, this gene is ubiquitously expressed in somatic tissues. The latter, combined with the finding that it is highly conserved in mouse and rat, suggests that the encoded protein is functionally important. An intronless pseudogene with high sequence similarity to this gene is located on chromosome 9.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: EKC/KEOPS complex subunit LAGE3; L antigen family member 3; L antigen family, member 3; Protein ESO-3; Protein ITBA2
基因别名: CVG5; DXS9879E; DXS9951E; ESO3; ITBA2; LAGE3; Pcc1
UniProt ID: (Human) Q14657
Entrez Gene ID: (Human) 8270