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产品信息
PA5-96186
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human LAMTOR5 (NP_0063932)
偶联物
形式
Liquid
浓度
2.07 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2807988
产品详细信息
Immunogen sequence: MEPGAGHLDG HRAGSPSLRQ ALCDGSAVMF SSKERGRCTV INFVPLEAPL RSTPRSRQVT EACGGEGRAV PLGSEPEWSV GGMEATLEQH LEDTMKNPSI VGVLCTDSQG LNLGCRGTLS DEHAGVISVL AQQAAKLTSD PTDIPVVCLE SDNGNIMIQK HDGITVAVHK MAS; Positive Samples: U-251MG, Mouse kidney; Cellular Location: Cytoplasm, Lysosome
靶标信息
HBXIP, also named as XIP, belongs to the HBXIP family. It is originally identified by its interaction with the C-terminus of hepatitis B virus (HBV) X protein (HBx). HBXIP is a regulator of centrosome dynamics and cytokinesis. HBXIP is able to up-regulate S100A4 though activating STAT4 and inducing DNA methylation of PTEN. HBXIP is a cellular 18kd protein and cytoplasm stain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HBV X-interacting protein; HBV X-interacting protein homolog; HBx-interacting protein; HBX-interacting protein homolog; hepatitis B virus x interacting protein; Hepatitis B virus X-interacting protein; hepatitis B virus x-interacting protein (9.6kD); hepatitis B virus X-interacting protein homolog; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5; MGC71071; Ragulator complex protein LAMTOR5
基因别名: 1110003H18Rik; HBXIP; LAMTOR5; XIP
UniProt ID: (Human) O43504, (Mouse) Q9D1L9
Entrez Gene ID: (Human) 10542, (Rat) 295357, (Mouse) 68576
regulation of cell size
viral genome replication
positive regulation of TOR signaling
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of GTPase activity
protein localization to lysosome
cellular response to amino acid stimulus
cell cycle arrest
response to virus
macroautophagy
