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产品信息
MA5-41625
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
C5
抗原
Recombinant protein Lecithin Cholesterol Acyltransferase. The antigen corresponds to amino acid range 290-433 of the target protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2899107
靶标信息
Lecithin: cholesterol acyltransferase (LCAT) is the plasma enzyme responsible for most HDL cholesteryl esters in human plasma. In species with cholesteryl ester transfer protein (CETP) it is also responsible for a significant proportion of VLDL and LDL cholesteryl esters. LCAT, through the esterification of cholesterol, plays a role in the reverse cholesterol transport pathway by facilitating the net movement of cholesterol from peripheral tissues back to the liver for excretion. LCAT deficiency results in low levels of plasma HDL, whereas a transgenic overexpression of LCAT results in increased plasma HDL concentrations.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 1-alkyl-2-acetylglycerophosphocholine esterase; Lecithin-cholesterol acyltransferase; PAF acetylhydrolase; phosphatidylcholine--sterol O-acyltransferase; Phosphatidylcholine-sterol acyltransferase; Phospholipid-cholesterol acyltransferase; Platelet-activating factor acetylhydrolase; testicular secretory protein Li 24
基因别名: LCAT
UniProt ID: (Human) P04180
Entrez Gene ID: (Human) 3931
phospholipid metabolic process
phosphatidylcholine biosynthetic process
cholesterol metabolic process
cholesterol transport
very-low-density lipoprotein particle remodeling
high-density lipoprotein particle remodeling
cholesterol esterification
lipoprotein metabolic process
lipoprotein biosynthetic process
cholesterol homeostasis
reverse cholesterol transport
phosphatidylcholine metabolic process
response to copper ion
response to glucocorticoid
regulation of high-density lipoprotein particle assembly
