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Product Details
PA5-21155
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 16 amino acid peptide near the amino terminus of human TYW4.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11155836
Product Specific Information
A suggested positive control is rat brain tissue lysate.
PA5-21155 can be used with blocking peptide PEP-1269.
Target Information
TYW4 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW4 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Leucine carboxyl methyltransferase 2; p21WAF1/CIP1 promoter-interacting protein; tRNA wybutosine-synthesizing protein 4; tRNA wybutosine-synthesizing protein 4 homolog; tRNA yW-synthesizing protein 4; tRNA yW-synthesizing protein 4 homolog; tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase; tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase; tRNA-Wybutosine-synthesizing protein 4; tRNA-yW synthesizing protein 4
Gene Aliases: D330024M17; KIAA0547; LCMT2; PPM2; TYW4
UniProt ID: (Human) O60294, (Mouse) Q8BYR1, (Rat) Q5XIA3
Entrez Gene ID: (Human) 9836, (Mouse) 329504, (Rat) 296098
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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