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产品信息
PA5-52911
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2643342
产品详细信息
Immunogen sequence: AVECAKTYLL FFPNDEVMNQ NLAYYAAMLG EEHTRSIGPR ESAKEYRQRS LLEKELLFFA YDVFGIPFVD PDSWTPEEVI PKRLQEKQKS ERETAVRISQ EIGNLMKEIE TLVEEKTKES LDVSRLT
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.
靶标信息
Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro- Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Growth suppressor 1; leprecan; Leprecan-1; leucine proline-enriched proteoglycan (leprecan) 1; Leucine- and proline-enriched proteoglycan 1; procollagen-proline 3-dioxygenase; Prolyl 3-hydroxylase 1
基因别名: GROS1; LEPRE1; OI8; P3H1; PSEC0109
UniProt ID: (Human) Q32P28
Entrez Gene ID: (Human) 64175
protein folding
negative regulation of cell proliferation
protein hydroxylation
peptidyl-proline hydroxylation
collagen metabolic process
regulation of protein secretion
protein stabilization
oxidation-reduction process
bone development
chaperone-mediated protein folding
negative regulation of post-translational protein modification
