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产品信息
PA5-52480
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2643344
产品详细信息
Immunogen sequence: LHYDYLQFAY YRVGEYVKAL ECAKAYLLCH PDDEDVLDNV DYYESLLDDS IDPASIEARE DLTMFVKRHK LESELIKSAA EGLGFSYTEP NYWIRYGGRQ DENRVPSGVN VEGAEVHGFS MGKKLSPKID RDLREGGPLL Y
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.
靶标信息
This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: leprecan-like 1; Leprecan-like protein 1; Myxoid liposarcoma-associated protein 4; procollagen-proline 3-dioxygenase 2; Prolyl 3-hydroxylase 2; prolyl 3-hydroxylase 3
基因别名: LEPREL1; MCVD; MLAT4; P3H2
UniProt ID: (Human) Q8IVL5, (Rat) Q4KLM6
Entrez Gene ID: (Human) 55214, (Rat) 288016
