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产品信息
PA5-83676
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2790829
产品详细信息
Immunogen sequence: PMHLQMREDM AKYRRMSGVR PQSFRDLETP PHWAAYDTGL ELLGRQEAGL ALPRLEEALQ GSLAQMESCR ADCEGPEEQQ GAEEEEDGAA SQGGLYEAIA GH
靶标信息
The protein encoded by this gene belongs to the leprecan family of proteoglycans, which function as collagen prolyl hydroxylases that are required for proper collagen biosynthesis, folding and assembly. This protein, like other family members, is thought to reside in the endoplasmic reticulum. Epigenetic inactivation of this gene is associated with breast and other cancers, suggesting that it may function as a tumor suppressor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: gene rich cluster, B; leprecan-like 2; Leprecan-like protein 2; procollagen-proline 3-dioxygenase; Prolyl 3-hydroxylase 3; Protein B
基因别名: BC016431; GRCB; HSU47926; LEPREL2; P3H3
UniProt ID: (Human) Q8IVL6, (Mouse) Q8CG70
Entrez Gene ID: (Human) 10536, (Rat) 297595, (Mouse) 14789
iron ion binding
procollagen-proline 3-dioxygenase activity
L-ascorbic acid binding
molecular_function
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
metal ion binding
dioxygenase activity
extracellular matrix glycoprotein
