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产品信息
PA5-21271
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region within amino acids 622 and 699 of LHR (Uniprot ID#P22888)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11152930
产品详细信息
Recommended positive controls: H1299.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
LHCGR encodes the receptor for both luteinizing hormone and choriogonadotropin. It is family 1 of G-protein coupled receptors, FSH/LSH/TSH superfamily, and its basic function is acting as luteinizing hormone/choriogonadotropin receptor (gonadotropin receptor). Regulating the development and function of Leyding cells in males. It also plays a role in male secondary sexual characterdevelopment. Mutations in this gonadotropinreceptor results in disorders of male secondary sexual characteristic development, such as familial male precocious puperty and male pseudohermaphtoditism.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: HCG receptor; hypergonadotropic hypogonadism; LH/CG-R; LHR; LSH-R; Luteinizing hormone receptor; Lutropin receptor; Lutropin-choriogonadotropic hormone receptor; lutropin/choriogonadotropin receptor
基因别名: Gpcr19-rs1; HHG; LCGR; LGR2; LH-R; LH/CG-R; LH/CGR; LHCGR; LHR; LHRHR; LSH-R; ULG5
UniProt ID: (Human) P22888, (Mouse) P30730
Entrez Gene ID: (Human) 3973, (Mouse) 16867
luteinizing hormone receptor activity
G-protein coupled peptide receptor activity
choriogonadotropin hormone receptor activity
choriogonadotropin hormone binding
signal transducer activity
G-protein coupled receptor activity
protein-hormone receptor activity
peptide hormone binding
identical protein binding
protein homodimerization activity
ATPase binding
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
phospholipase C-activating G-protein coupled receptor signaling pathway
male gonad development
hormone-mediated signaling pathway
ovulation cycle process
male genitalia development
positive regulation of inositol trisphosphate biosynthetic process
luteinizing hormone signaling pathway
positive regulation of cAMP-mediated signaling
cognition
cellular response to gonadotropin stimulus
ovarian follicle development
protein targeting to lysosome
signal transduction
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
spermatogenesis
female gonad development
positive regulation of calcium ion transport into cytosol
development of secondary male sexual characteristics
positive regulation of hormone biosynthetic process
arachidonic acid secretion
positive regulation of calcium-mediated signaling
positive regulation of release of sequestered calcium ion into cytosol
uterus development
seminiferous tubule development
regulation of steroid hormone biosynthetic process
