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LHX2 Antibody (PA5-78287) in IHC (F)
LHX2 Polyclonal Antibody detects LHX2 protein expression by immunohistochemical analysis. Sample: Frozen sectioned adult mouse retina. Green: LHX2 protein stained by LHX2 Polyclonal Antibody (Product # PA5-78287) diluted at 1:250. Red: beta Tubulin 3/ TUJ1, stained by beta Tubulin 3/ TUJ1 antibody [GT11710] diluted at 1:250. Blue: Fluoroshield with DAPI .
Product Details
PA5-78287
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human LHX2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.97 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2736088
Product Specific Information
Positive Control: 293T, A431, HeLa, HepG2, Neuro 2A, GL261, C8D30, NIH-3T3, BCL-1, Raw264.7, C2C12, mouse brain, mouse eye
Predicted Reactivity: Pig (98%), Chicken (81%), Rhesus Monkey (98%), Bovine (98%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Homeobox protein LH-2; LIM homeo box protein 2; LIM homeobox protein 2; LIM HOX gene 2; LIM/homeobox protein Lhx2; MGC138390
Gene Aliases: ap; apterous; hLhx2; Lh-2; LH2; LH2A; LHX2; Lim2
UniProt ID: (Human) P50458, (Mouse) Q9Z0S2
Entrez Gene ID: (Human) 9355, (Mouse) 16870, (Rat) 296706
transcription factor activity, RNA polymerase II transcription factor binding
chromatin binding
zinc ion binding
sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
DNA binding
protein binding
metal ion binding
helix-turn-helix transcription factor
homeodomain transcription factor
DNA-binding transcription factor
gene-specific transcriptional regulator
neural tube closure
hair follicle development
transcription, DNA-templated
axon guidance
mesoderm development
dorsal/ventral pattern formation
olfactory bulb development
telencephalon regionalization
cerebral cortex development
maintenance of epithelial cell apical/basal polarity
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
axon extension
retina development in camera-type eye
negative regulation of transcription regulatory region DNA binding
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
nervous system development
brain development
telencephalon development
neurogenesis
neuron differentiation
anatomical structure formation involved in morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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