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产品信息
PA5-120697
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human LLGL1 (NP_004131.3).
偶联物
形式
Liquid
浓度
1.10 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914269
产品详细信息
Positive test controls include: OVCAR3, A-431, U-251MG, Mouse testis, Mouse brain, Rat testis.
Immunogen sequence: MMKFRFRRQG ADPQREKLKQ ELFAFNKTVE HGFPNQPSAL AFDPELRIMA IGTRSGAVKI YGAPGVEFTG LHRDAATVTQ MHFLTGQGRL LSLLDDSSLH LWEIVHHNGC AHLEEALSFQ LPSRPGFDGA SAPLSLTRVT VVLLVAAGDI AALGTEGSSV FFLDVTTLTL LEGQTLAPGE VLRSVPDDYR
靶标信息
LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DLG4; Hugl protein; Hugl-1; Human homolog to the D-lgl gene protein; lethal giant larvae homolog 1; lethal giant larvae homolog 1, scribble cell polarity complex component; Lethal(2) giant larvae protein homolog 1; LLGL; Mgl-1; Mlgl
基因别名: AI325176; DLG4; HUGL; HUGL-1; HUGL1; Lgl1; LLGL; LLGL1; Llglh; Mgl1; Rgl-1; Rgl1
UniProt ID: (Human) Q15334, (Mouse) Q80Y17
Entrez Gene ID: (Human) 3996, (Rat) 54265, (Mouse) 16897
protein complex assembly
exocytosis
Golgi to plasma membrane transport
axonogenesis
regulation of Notch signaling pathway
regulation of exocytosis
neurogenesis
cortical actin cytoskeleton organization
regulation of establishment or maintenance of cell polarity
positive regulation of GTPase activity
regulation of protein secretion
establishment of spindle orientation
maintenance of apical/basal cell polarity
brain development
