Invitrogen

LLGL2 Polyclonal Antibody

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LLGL2 Antibody (PA5-120204) in WB

Western blot analysis of LLGL2 in extracts of various cell lines. Samples were incubated with LLGL2 Polyclonal antibody (Product # PA5-120204) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

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产品信息

PA5-120204

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide corresponding to a sequence within amino acids 938-1027 of mouse LLGL2 (NP_6634132)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.96 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2913776

产品详细信息

Positive test controls include: Mouse lung, Mouse testis, Rat lung. The target is usually found in the following locations: Cytoplasm.

Immunogen sequence: DSTKAKKHNR PSNGNGTGLK MTSSGHVRNS KSQSDGDEKK PGPVMEHALL NDAWVLKEIQ STLEGDRRSY GNWHPHRVAV GCRLSNGEAE

靶标信息

LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。