Invitrogen

LOXL3 Polyclonal Antibody

LOXL3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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LOXL3 Antibody (PA5-145269) in IHC (P)

Immunohistochemistry (Paraffin) analysis of LOXL3 in Human Kidney Tissue. Samples were incubated in LOXL3 polyclonal antibody (Product # PA5-145269) using a dilution of 20 μg/mL followed by HRP-Linked Caprine Anti-Rabbit IgG at a dilution of 2 µg/mL and DAB staining.

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产品信息

PA5-145269

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.01-2 µg/mL

免疫组化（石蜡） (IHC (P))

5-20 µg/mL

产品规格

种属反应

Human, Mouse, Pig, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant Human LOXL3 protein, Thr519-Asn726 (Accession #P58215)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.05% Proclin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_3093537

靶标信息

LOXL3 is a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

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