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LOXL4 Antibody (PA5-115520) in ICC/IF
Immunocytochemistry analysis of LOXL4 in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115520). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
产品信息
PA5-115520
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human LOXL4(Accession Q96JB6), corresponding to amino acid residues V130-E180.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2900156
产品详细信息
Antibody detects endogenous levels of total LOXL4.
靶标信息
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ21889; Lysyl oxidase homolog 4; lysyl oxidase related C; lysyl oxidase-like 4 pseudogene; Lysyl oxidase-like protein 4; Lysyl oxidase-related protein C
基因别名: 4833426I20Rik; LOXC; LOXL4
UniProt ID: (Human) Q96JB6, (Mouse) Q924C6
Entrez Gene ID: (Human) 84171, (Rat) 309380, (Mouse) 67573
