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产品信息
PA5-97932
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Lysophosphatidic acid receptor 4 protein (1-43AA)
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_2812546
靶标信息
EDG4 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG4 is expressed in testes, ovarian tumor, and leukocyte containing tissues.
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生物信息学
蛋白别名: G protein-coupled receptor 23; G-protein coupled receptor 23; LPA receptor 4; LPA-4; LPA4 Receptor; Lysophosphatidic acid receptor 4; P2Y purinoceptor 9; P2Y5-like receptor; P2Y9; Purinergic receptor 9
基因别名: 5730485F04Rik; GPR23; LPA4; LPAR4; P2RY9; P2Y5-LIKE; P2Y9
UniProt ID: (Human) Q99677, (Mouse) Q8BLG2
Entrez Gene ID: (Human) 2846, (Mouse) 78134
