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Immunogen sequence: LATSPIPTED QFFKDIDTPL VKSGGDETPS QSSDISHVLE TETIFTPSSV KKKKRRRKKY KQDSKKEEQA ASAAAEDTCD VGVSSDDDKG AQAARGSSNA SLKEEECKEP LLFHSGDHYP LSDGDWSP
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 80%.
Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Lipin-2; Phosphatidate phosphatase LPIN2
Gene Aliases: KIAA0249; LPIN2
UniProt ID: (Human) Q92539
Entrez Gene ID: (Human) 9663
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