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产品信息
PA5-52860
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2643468
产品详细信息
Immunogen sequence: TRKKSEEYSV TNTDETVVPP DVPSYLSSQG TLSDRQETVV RTEGGPQANG HIESNGVCPR DASHFPEPDT HSVACRQPKL CAGSAYHKEP WKAMEKAEGT PGPHKMEHGG RVVCSDCNTE VDCYS
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 74%.
靶标信息
LRIG1 protein Q96JA1 is coded by a gene on a chromosome band 3p14.3, this region is known to be deleted in various human cancers. LRIG1 is considered to be a tumor suppressor gene in humans. LRIG1 is an integral cell-surface membrane protein that is expressed by specific cells in various human tissues and that its 143-kDa form might be cleaved into 111-kDa and 32-kDa fragments. The LRIG1 protein may inhibit the growth of tumors of glial cells and the down-regulation of the LRIG1 gene may be involved in the development and progression of the tumor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp586O1624; leucine-rich repeat protein LRIG1; leucine-rich repeats and immunoglobulin like domains 1; leucine-rich repeats and immunoglobulin-like domains 1; Leucine-rich repeats and immunoglobulin-like domains protein 1; LIG-1; ortholog of mouse integral membrane glycoprotein LIG-1
基因别名: LIG-1; LIG1; LRIG1
UniProt ID: (Human) Q96JA1
Entrez Gene ID: (Human) 26018
