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LRIG1 Antibody (PA5-88302) in WB
Western blot analysis of LRIG1 in extracts of various cell lines. Samples were incubated with LRIG1 Polyclonal antibody (Product # PA5-88302) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-88302
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 816-1093 of human LRIG1 (NP_0563562)
偶联物
形式
Liquid
浓度
0.32 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2804813
产品详细信息
Immunogen sequence: YQTRKKSEEY SVTNTDETVV PPDVPSYLSS QGTLSDRQET VVRTEGGPQA NGHIESNGVC PRDASHFPEP DTHSVACRQP KLCAGSAYHK EPWKAMEKAE GTPGPHKMEH GGRVVCSDCN TEVDCYSRGQ AFHPQPVSRD SAQPSAPNGP EPGGSDQEHS PHHQCSRTAA GSCPECQGSL YPSNHDRMLT AVKKKPMASL DGKGDSSWTL ARLYHPDSTE LQPASSLTSG SPERAEAQYL LVSNGHLPKA CDASPESTPL TGQLPGKQRV PLLLAPKS; Positive Samples: Raji, HeLa; Cellular Location: Membrane, Single-pass type I membrane protein
靶标信息
LRIG1 protein Q96JA1 is coded by a gene on a chromosome band 3p14.3, this region is known to be deleted in various human cancers. LRIG1 is considered to be a tumor suppressor gene in humans. LRIG1 is an integral cell-surface membrane protein that is expressed by specific cells in various human tissues and that its 143-kDa form might be cleaved into 111-kDa and 32-kDa fragments. The LRIG1 protein may inhibit the growth of tumors of glial cells and the down-regulation of the LRIG1 gene may be involved in the development and progression of the tumor.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp586O1624; leucine-rich repeat protein LRIG1; leucine-rich repeats and immunoglobulin like domains 1; leucine-rich repeats and immunoglobulin-like domains 1; Leucine-rich repeats and immunoglobulin-like domains protein 1; LIG-1; ortholog of mouse integral membrane glycoprotein LIG-1
基因别名: LIG-1; LIG1; LRIG1
UniProt ID: (Human) Q96JA1
Entrez Gene ID: (Human) 26018
