Invitrogen

LRP1 Monoclonal Antibody (A2MR-alpha-2)

LRP1 Antibody in Immunocytochemistry (ICC/IF)

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LRP1 Antibody (37-3800) in ICC/IF

Immunofluorescence analysis of Prolow-density lipoprotein receptor-related protein 1 was performed using 70% confluent log phase U-87 MG and SK-BR-3 cells. The cells were fixed with 4% paraformaldehyde for 5 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 2% BSA for overnight at room temperature. The cells were labeled with LRP1 Monoclonal Antibody (A2MR-alpha-2) (Product # 37-3800) at 1:100 dilution in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Donkey anti-Mouse IgG (H+L) Highly... View More

LRP1 Antibody in Immunohistochemistry (Frozen) (IHC (F))

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LRP1 Antibody — Antibody specificity was demonstrated by detection of differential basal expression of the target across cell models owing to their inherent genetic constitution. Immunofluorescence analysis using Anti-LRP1 Monoclonal Antibody (A2MR-alpha-2) (Product # 37-3800), shows expression in U-87 MG in comparison to SK-BR-3. {RE}

产品信息

37-3800

应用

建议稀释比

已发表文章

免疫印迹 (WB)

Assay-dependent

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免疫组化 (IHC)

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免疫组化（石蜡） (IHC (P))

1:100

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免疫组化（冰冻） (IHC (F))

Assay-dependent

免疫细胞化学 (ICC/IF)

1:100

流式细胞分析 (Flow)

Assay-dependent

产品规格

种属反应

Human, Mouse

已发表种属

Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

A2MR-alpha-2

抗原

Purified human CD91 alpha chain protein.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

0.1% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2533314

产品详细信息

37-3800 has been successfully used in immunohistochemistry analysis of LRP1 in mouse E16.5 frozen lung sections.

靶标信息

The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

The significance of heat-shock protein gp96 and its receptors' CD91 and Toll-like receptor 4 expression at the maternal foetal interface.

American journal of reproductive immunology (New York, N.Y. : 1989)

Gulic T,Laskarin G,Redzovic A,Eminović S,Haller H,Rukavina D

37-3800 was used in immunohistochemistry - paraffin section to study the expression of gp96, CD91 and TLR4 at the maternal-fetal interface and the clinical significance

Mon Jul 01 00:00:00 UTC 2013

Distribution of the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein in human tissues.

Cell and tissue research

Moestrup SK,Gliemann J,Pallesen G

Tue Sep 01 00:00:00 UTC 1992

Distribution of the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein in human tissues.

Cell and tissue research

Moestrup SK,Gliemann J,Pallesen G

Tue Sep 01 00:00:00 UTC 1992

生物信息学

蛋白别名: A2MR; alpha 2-macroglobulin receptor; Alpha-2-macroglobulin receptor; APOER; Apolipoprotein E receptor; CD91; FLJ16451; lipoprotein receptor-related protein; low density lipoprotein receptor-related protein 1; LRP-1; lrp1; MGC88725; Prolow-density lipoprotein receptor-related protein 1; TbetaR-V/LRP-1/IGFBP-3 receptor; type V tgf-beta receptor

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基因别名: A2MR; AI316852; APOER; APR; b2b1554Clo; CD91; IGFBP3R; LRP; LRP1; LRP1A; TGFBR5

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UniProt ID: (Human) Q07954, (Mouse) Q91ZX7

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Entrez Gene ID: (Human) 4035, (Mouse) 16971

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