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LRP8 Antibody (MA5-38208) in WB
Western blot was performed using LRP8 Recombinant Rabbit Monoclonal Antibody (ARC1730) (Product # MA5-38208) and a ~100 kDa band corresponding to LRP8 was observed across Mouse testis, Rat testis, Mouse brain and Rat brain. Whole cell extracts (30 µg lysate) of Mouse Testis (Lane 1), Rat Testis (Lane 2), Mouse Brain (Lane 3), Rat Brain (Lane 4), Rat Spleen (Lane 5) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0322BOX), 12 well. Resolved proteins were then transferred onto a nitrocellulose membrane (Product # I... View More
产品信息
MA5-38208
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
0V1R8
抗原
A synthetic peptide corresponding to a sequence within amino acids 864-963 of human ApoER2/LRP8 (Q14114)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2898125
产品详细信息
Positive Samples: U-87MG, Mouse testis, Rat testis
Immunogen sequence: PVYRKTTEEE DEDELHIGRT AQIGHVYPAA ISSFDRPLWA EPCLGETREP EDPAPALKEL FVLPGEPRSQ LHQLPKNPLS ELPVVKSKRV ALSLEDDGLP
靶标信息
Apolipoprotein E receptor 2 (ApoER2) is an NMDA associated protein found in neurons. It participates in important functions from guiding neurons in the embryonic brain to regulating synaptic signaling. It is also involved in debilitating neurodegenerative diseases such as schizophrenia and Alzheimer's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ApoE receptor 2; Apolipoprotein E receptor 2; low density lipoprotein receptor relative, 8 ligand binding repeats, brain; low density lipoprotein receptor-related protein 8, apolipoprotein e receptor; Low-density lipoprotein receptor-related protein 8; LRP-8
基因别名: 4932703M08Rik; AA921429; AI848122; APOER2; HSZ75190; Lr8b; LRP-8; LRP8; MCI1
UniProt ID: (Human) Q14114
Entrez Gene ID: (Human) 7804, (Rat) 362558, (Mouse) 16975
transmembrane signaling receptor activity
low-density lipoprotein receptor activity
calcium ion binding
protein binding
high-density lipoprotein particle binding
kinesin binding
very-low-density lipoprotein particle receptor activity
apolipoprotein binding
reelin receptor activity
glycoprotein binding
calcium-dependent protein binding
apolipoprotein
negative regulation of transcription from RNA polymerase II promoter
retinoid metabolic process
proteolysis
lipid metabolic process
endocytosis
receptor-mediated endocytosis
signal transduction
cytokine-mediated signaling pathway
ammon gyrus development
cerebral cortex development
positive regulation of CREB transcription factor activity
reelin-mediated signaling pathway
response to drug
positive regulation of peptidyl-tyrosine phosphorylation
modulation of synaptic transmission
positive regulation of dendritic spine morphogenesis
positive regulation of protein tyrosine kinase activity
cellular response to growth factor stimulus
cellular response to cholesterol
positive regulation of dendrite development
hippocampus development
layer formation in cerebral cortex
positive regulation of protein kinase activity
