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A recommended positive control is human prostate tissue lysate.
The LRRC26 protein was initially identified as a cytokeratin-associated protein whose expression was elevated in multiple cancer cell lines and cancer specimens as well in normal prostate and salivary gland tissues. LRRC26 was later found to negatively regulate the NF-kappaB activation and suppresses tumor growth and metastasis. LRRC26 can also act to selectively alter the efficacy of large conductance calcium-activated K (BK) channels.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BK channel auxiliary gamma subunit LRRC26; BK channel auxilliary gamma subunit LRRC26; cytokeratin associated protein; Cytokeratin-associated protein in cancer; Leucine-rich repeat-containing protein 26
基因别名: bA350O14.10; CAPC; LRRC26
UniProt ID: (Human) Q2I0M4
Entrez Gene ID: (Human) 389816