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LRRC8A Antibody (PA5-49209) in WB
Western blot analysis of LRRC8A in various lysates. Samples were incubated with LRRC8A polyclonal antibody (Product # PA5-49209) using a dilution of 1:2,000 followed by Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at a dilution of 1:10,000. Lysates/proteins: 20 µg per lane. Lane 1: 293T/17 whole cell lysate; Lane 2: mouse kidney lysate. Predicted band size: 94 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
产品信息
PA5-49209
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 782-810 amino acids from the C-terminal region of human LRRC8A.
偶联物
形式
Liquid
浓度
0.4 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2634665
产品详细信息
Predicted to react with mouse and rat based on sequence homology.
靶标信息
Essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8A constitutes a pore-forming subunit or whether it is closely associated with the pore and mediates channel properties such as ion selectivity. Involved in B-cell development: required for the pro-B cell to pre-B cell transition. Also required for T-cell development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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