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Immunogen sequence: RSVPSSLQAS AREESRSELS GRTTRTDGSS VGGTFSRATT LSRGQSRKKK RKPKVDYQQV FTRHINQIFI RGENVLLV
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
LSm11 is a 360 amino acid protein that localizes to the nucleus and belongs to the LSm subfamily of snRNP Sm proteins. Containing an N-terminal domain that is necessary for pre-mRNA cleavage, LSm11 functions to binds specifically to U7 snRNA and is thought to play a role in cell cycle regulation and cell growth. The gene encoding LSm11 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ38273; U7 snRNA-associated Sm-like protein LSm11
基因别名: LSM11
UniProt ID: (Human) P83369
Entrez Gene ID: (Human) 134353