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产品信息
PA5-106493
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human LTB(Accession Q06643), corresponding to amino acid residues P191-V241.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2854162
产品详细信息
Antibody detects endogenous levels of total TNFC.
靶标信息
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: LT-beta; lymphotoxin B; lymphotoxin beta (TNF superfamily, member 3); Lymphotoxin-beta; TNF superfamily member 3; TNF-C; Tumor necrosis factor C; tumor necrosis factor ligand 1C; Tumor necrosis factor ligand superfamily member 3
基因别名: LTB; p33; TNFC; TNFSF3; TNLG1C
UniProt ID: (Human) Q06643
Entrez Gene ID: (Human) 4050, (Rat) 361795
